What I like about the show is the way that Bob doesn't appear to be the primary focus all the time where usually Peter Griffin, Cleveland Brown, and Stan Smith are in their shows. I like it for two reasons: 1) it allows Bob's family to shine and grow in their own way on the show and with the audience, and 2) I've never been a huge fan of H. Jon Benjamin's voice.
As most would agree, I think Louise is great, but I think what helps that is her brother Gene. He sets her up a lot and also supports her eccentric behavior as if it was normal. I like how they both team up against their oldest sister. Where most kids look up to the elder sibling for guidance, none of that is happening which opens a lot of doors for comedy.
Bob Burger's currently airs on FOX on Sunday 8:30/7:30c
http://www.fox.com/bobsburgers/