The issue begins with a flashback to Valencia 1094, where Demona saves Angelika from De Ablo who is trying to obtain gargoyle blood to create an immortality elixir called "Elixir Vitae". Demona frees her and they escape.
We return to the present labeled as "now" in Manhattan where Angela, Broadway and Lex are squaring up against the Fantastic Four. Introductions happen and everyone stands down. Lex mentions seeing their flare. I had to refer to the comic “Demona #0” where the Gargoyles initially see the flare after dealing with Demona stealing. In that comic, Sue says, "You weren't actually the three heroes I was summoning", so at this point we don't know who the FF were summoning, but no one else shows up to assist them. The issue at hand - the FF need help with the "Grey Gargoyle" aka Paul Duval who is turning people to stone on the Brooklyn Bridge including two of our favorites Brendan and Margot.
Meanwhile, an unknown yellow gargoyle with purple armor is being tortured and escapes some sort of containment device, mentioning allowed that he has to warn someone.
Elsewhere, Tony Stark is giving David Xanatos a tour of his facility where we see a collection of Iron Man suits and a large containment tank filled with blue liquid. Xanatos leaves.
Back to the bridge, the Gargoyles and FF attempt to stop Duval. He uses some kind of smoke grenade that turns everyone to stone in the blast radius including Angela, Mr. Fantastic, and other humans on the bridge. Everyone else is okay as Sue traps Duval in a force field.
Back at Stark Industries, Xanatos in his Armored Gargoyle suit, comes and steals the large containment tank. As Iron Man attempts to stop him, Xanatos summons his Steel Clan which allows him to escape.
We then go to Castle Wyvern where that yellow gargoyle with purple armor introduces himself to the rest of the clan as "The Gargoyle" aka Isaac Christians. He warns them of an alchemist named Diablo is attempting to create Elixir Vitae. Lex returns to the castle to inform them of the situation on the Brooklyn Bridge.
Xanatos delivers the large containment unit to Diablo who has promised Xanatos some Elixir Vitae for his services. Diablo monologues to the containment unit, letting the reader know that he was behind everything that has happened thus far: he let Isaac Christians free, he set Duval on his mission, and he got what was in the containment tank. He did this all with the intent of capturing a gargoyle to get its blood.
Back at the bridge, the police arrive to protect those in stone. Iron Man shows up to assist as well, and Goliath has Hudson and Coldfire to stay there to help if needed. Everyone else departs away from the bridge to some other location in New York. Suddenly, Diablo uses a portal to steal Angela. Sue and Broadway follow while Sue uses her invisibility powers. Everyone else battles "Dragon Man" who was the one trapped in the containment tank. It turns out he's an AI and Lex easily shuts him down using the FF's electromagnetic pulse gun on their vehicle.
Meanwhile, Diablo uses a spell to turn everyone back normal who had been turned to stone, so he can take Angela's blood. He also sense's Sue and Broadway's presence and captures them with some sort of green energy ropes.
Demona shows up and uses "Fulminous Venite" to defeat Diablo. Broadway and Angela chain up Diablo as Demona disappears.
Later, Reed mentions being able to reprogram Dragon Man. Reed gets a call from Tony Stark. Xanatos tells Goliath and Brooklyn that he had no idea that Angela would be put in harm's way. Xanatos then gets a call from Tony Stark. Goliath and Brooklyn welcome Isaac to the Clan.
We have a nice little happy ending showing the FF clan all together at home as well as the Gargoyle Clan all together at their home (including Edwardo which means this takes place before the events of "Gargoyles Quest").
The final shot shows that the Baxter Building and the Eyrie Building are just a few skyscrapers away (leaving this open for a future adventure/team up).
